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Low Carb Keto Science
  • Home
  • Research & You
    • Why this website?
    • Pub Med & PubVenn
  • Body Systems
    • The Human Body
    • Cardiovascular
    • Digestive
    • Endocrine
    • Fat
    • Immune
    • Integumentary
    • Lymphatic
    • Skeletal
    • Muscular
    • Nervous
    • NS Brain
    • Reproducton :Male
    • Reproduction: Female
    • Respiratory
    • Sensory
    • Sensory - Sight
    • Sensory - Sound
    • Sensory - Smell
    • Sensory -Taste
    • Sensory- Touch
    • Urinary
    • Subsystems
    • Subsystems2
  • Life Stages
    • Pregnancy
    • Fetus
    • Infancy
    • Toddlerhood
    • Childhood
    • Adolescent
    • Early Adulthood
    • Middle Adulthood
    • Late Adulthood
    • Geriatric

the fat system

The Fat System

 The "fat system" typically refers to the body's adipose tissue, which is  composed of specialized cells called adipocytes that store and release  fat. Adipose tissue serves several important functions in the body,  including energy storage, insulation, and hormone regulation. There are  two main types of adipose tissue: white adipose tissue (WAT) and brown  adipose tissue (BAT). White adipose tissue is the primary form of fat  storage in the body and is found in larger deposits throughout the body,  including under the skin (subcutaneous fat) and around internal organs  (visceral fat). Brown adipose tissue, on the other hand, is more  metabolically active and is involved in generating heat to maintain body  temperature. The balance between these two types of adipose tissue and  their respective functions is important for overall metabolic health.  Dysregulation of the fat system, such as excessive accumulation of  visceral fat or dysfunction of brown adipose tissue, can contribute to  various metabolic disorders, including obesity, insulin resistance, and  cardiovascular disease. Therefore, maintaining a healthy balance of  adipose tissue and supporting its proper function is essential for  overall health and well-being. 

Hall marks of too much fat

  

  1. Obesity: Excessive accumulation of adipose tissue, particularly visceral fat, can lead to obesity. Obesity is associated with an increased risk of numerous health problems, including type 2 diabetes, cardiovascular disease, fatty liver disease, and certain cancers.
  2. Insulin Resistance: Dysregulation of adipose tissue function can lead to insulin resistance, a condition where cells become less responsive to the effects of insulin. Insulin resistance is a key factor in the development of type 2 diabetes and metabolic syndrome.
  3. Inflammation: Adipose tissue can release inflammatory molecules called adipokines, which can contribute to chronic low-grade inflammation. This inflammation is linked to the development of various diseases, including cardiovascular disease, insulin resistance, and inflammatory conditions.
  4. Lipid Metabolism Disorders: Dysfunction in adipose tissue can disrupt lipid metabolism, leading to abnormal levels of cholesterol and triglycerides in the blood. Dyslipidemia is a significant risk factor for cardiovascular disease.
  5. Hormonal Imbalance: Adipose tissue produces hormones and cytokines that regulate various physiological processes, including appetite, metabolism, and inflammation. Dysfunction in adipose tissue can lead to hormonal imbalances, which may contribute to metabolic disorders and other health issues.
  6. Lipodystrophy: Lipodystrophy is a rare disorder characterized by abnormal or degenerative conditions of adipose tissue. This can result in abnormal fat distribution, insulin resistance, and metabolic complications.
  7. Adipose Tissue Inflammation: Inflammatory responses within adipose tissue, known as adipose tissue inflammation, can lead to the recruitment of immune cells and the release of pro-inflammatory cytokines. Chronic adipose tissue inflammation is associated with insulin resistance and metabolic dysfunction.

Addressing these issues often involves lifestyle modifications such as adopting a healthy diet, engaging in regular physical activity, and maintaining a healthy weight. In some cases, medications or surgical interventions may be necessary to manage complications associated with fat system dysfunction.

Obesity

Obesity

 Obesity exerts a profound impact on virtually every system of the human  body, significantly increasing the risk of various chronic diseases and  impairing overall health. In the cardiovascular system, obesity  contributes to hypertension, dyslipidemia, atherosclerosis, and  increased risk of heart disease and stroke. It also strains the  respiratory system, leading to obstructive sleep apnea, asthma, and  decreased lung function. Obesity is closely linked to insulin  resistance, type 2 diabetes, and metabolic syndrome, affecting glucose  metabolism and promoting systemic inflammation. Furthermore, obesity  increases the risk of fatty liver disease, gallstones, and  gastrointestinal disorders. Musculoskeletal complications include  osteoarthritis, back pain, and reduced mobility. Obesity also impacts  reproductive health, increasing the risk of infertility, menstrual  irregularities, and pregnancy complications. Psychosocially, obesity can  lead to depression, low self-esteem, and impaired quality of life.  Ultimately, obesity poses a significant burden on healthcare systems,  contributing to increased morbidity, mortality, and healthcare costs.  Addressing obesity through lifestyle modifications, behavioral  interventions, and medical treatments is crucial in mitigating its  adverse effects and improving overall health outcomes. 

visceral fat

Visceral Fat

 Visceral fat, also known as intra-abdominal or deep fat, is the type of  fat that surrounds the abdominal organs, such as the liver, pancreas,  and intestines. While hyperinsulinemia isn't a direct cause of visceral  fat accumulation, it is often associated with insulin resistance and  metabolic syndrome, which are risk factors for increased visceral  adiposity. Insulin resistance leads to elevated levels of insulin in the  blood, which can promote the storage of fat, particularly around  visceral organs. Additionally, insulin resistance is associated with  dysregulation of lipid metabolism and increased production of  inflammatory cytokines, which may further contribute to visceral fat  deposition. Visceral fat is metabolically active and releases  inflammatory substances and hormones that can increase the risk of  various health problems, including type 2 diabetes, cardiovascular  disease, and fatty liver disease. Managing hyperinsulinemia through  lifestyle modifications, such as regular physical activity, healthy  eating habits, and weight management, can help reduce visceral fat  accumulation and improve metabolic health. Additionally, targeted  interventions to improve insulin sensitivity may also be beneficial in  reducing visceral fat and mitigating associated health risks. 

Weight gain

Weight gain

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PENDING 2

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